Post Reply 
 
Thread Rating:
  • 0 Vote(s) - 0 Average
  • 1
  • 2
  • 3
  • 4
  • 5
Weight loss reverses fatty liver disease
02-22-2009, 09:15 AM
Post: #1
Weight loss reverses fatty liver disease
Sunday, February 22, 2009
LAHORE: Researchers found that weight loss of at least nine percent of body weight helped patients reverse a fatty liver disease known as nonalcoholic steatohepatitis or NASH. The finding comes from a study of the diet drug orlistat (also known as Xenical and Alli), which did not itself improve liver disease.

Brent Neuschwander-Tetri, hepatologist at Saint Louis University (SLU) Liver Centre and study co-author, said: “It’s a helpful study because we can now give patients a benchmark, a line they need to cross to see improvement.”

The study looked at patients with NASH, characterised by excessive fat, causing inflammation and damage in the liver.

Researchers set out to see if orlistat, which limits fat absorption, along with calorie restriction would lead to weight loss and check liver disease in overweight patients with NASH, which was determined by a liver biopsy.

Fifty patients participated in the study, with all instructed to consume a 1,400 calorie diet and vitamin E, and half also receiving orlistat for 36 weeks, at which time liver biopsies were repeated.

While orlistat itself was not linked directly to improved liver health, weight loss was, and, further, researchers were able to pin-point the percentage of weight loss needed to improve liver damage.

Patients who lost five percent or more of body weight over nine months showed improvement in insulin resistance and steatosis (fat accumulation in the liver), and those who lost at least nine percent showed reversal of their liver damage, said an SLU release. The data about the drug orlistat was less clear. Those in the orlistat group lost 8.3 percent body weight and those in the other group lost six percent body weight, not a statistically significant difference. As for liver disease, orlistat did not itself improve liver enzymes, measures of insulin resistance or reverse liver damage.

http://www.thenews.com.pk/daily_detail.asp?id=163957
Find all posts by this user
Quote this message in a reply
Post Reply 


Possibly Related Threads...
Thread: Author Replies: Views: Last Post
  Land for road to Bahria Enclave: Official causes Rs5bn loss to CDA Salman 0 8,890 05-29-2013 11:45 AM
Last Post: Salman
  Development at a great loss Salman 0 3,699 07-16-2012 12:12 PM
Last Post: Salman
  Energy crisis causing irreparable loss to national economy: CM Salman 0 4,105 04-07-2012 12:15 PM
Last Post: Salman
  Liver transplant institute being set up in city: Shahbaz Lahore_Real_Estate 0 3,410 12-17-2011 12:33 PM
Last Post: Lahore_Real_Estate
  Purchase of animals on weight basis picks up in city Lahore_Real_Estate 0 3,629 11-13-2010 01:34 PM
Last Post: Lahore_Real_Estate
  First-ever liver transplant centre in 2011: PM Lahore_Real_Estate 0 3,187 11-05-2010 01:23 PM
Last Post: Lahore_Real_Estate
  Poultry industry suffered Rs eight billion loss due to floods Lahore_Real_Estate 0 4,297 10-28-2010 03:16 PM
Last Post: Lahore_Real_Estate
  Non-completion of housing schemes: OPF suffers Rs 718.78 million loss Lahore_Real_Estate 0 3,598 10-11-2010 12:04 PM
Last Post: Lahore_Real_Estate
  Procurement of land near Lahore: NICL caused Rs 1.045 billion loss to exchequer: NAB Lahore_Real_Estate 0 4,121 08-30-2010 12:41 PM
Last Post: Lahore_Real_Estate
  ATT Affecting Pak Economy Badly; Causing Loss of Billions of Dollars LRE 0 4,363 07-13-2010 12:25 AM
Last Post: LRE
  EOBI Face Heavy Loss for investing in BOP LRE 0 4,959 06-02-2010 01:29 AM
Last Post: LRE
  Pak Suzuki reports loss of Rs17.61m Lahore_Real_Estate 0 3,694 04-28-2010 01:04 PM
Last Post: Lahore_Real_Estate
  Gwdar Port: Rs 120 Million Loss in 8 Months LRE 0 3,686 03-27-2010 11:33 PM
Last Post: LRE
  Capital to have modern Liver Transplant Centre LahoreEstate 0 3,803 11-23-2009 03:39 AM
Last Post: LahoreEstate
  Reduce Weight by Eating as much as you want ! LRE 0 3,119 11-21-2009 01:32 PM
Last Post: LRE
  High fibre diets bad for controlling diabetes, heart disease Naveed Yaseen 0 4,612 11-15-2009 06:14 AM
Last Post: Naveed Yaseen
  PIA suffered Rs 76.54 billion loss till June 30: Mukhtar Naveed Yaseen 0 3,525 11-08-2009 06:43 AM
Last Post: Naveed Yaseen
  Longer sleep linked with lower risk of heart disease factor LahoreEstate 0 3,795 11-08-2009 06:14 AM
Last Post: LahoreEstate
  Aspirin does not prevent cardiovascular disease deaths: research Naveed Yaseen 0 4,468 11-05-2009 10:54 AM
Last Post: Naveed Yaseen
  Former chairman Pak Steel caused Rs 22 billion loss by embezzlement: SC told Naveed Yaseen 0 3,542 10-31-2009 08:05 AM
Last Post: Naveed Yaseen

Forum Jump:


User(s) browsing this thread: 1 Guest(s)